The neuronal gene Arc encodes a repurposed retrotransposon gag protein that mediates intercellular RNA transfer

2018
Written By Stellate Comms

Pastuzyn ED, Day CE, Kearns RB, Kyrke-Smith M, Taibi AV, McCormick J, Yoder N, Belnap DM, Erlendsson S, Morado DR, Briggs JAG, Feschotte C, Shepherd JD (2018). Cell, 172:1-2.

Stellate Comms https://stellatecomms.com
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Arc - an endogenous neuronal retrovirus?
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Activity-dependent Arc expression and homeostatic synaptic plasticity are altered in neurons from a mouse model of Angelman syndrome